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药物或治疗策略。</p>
<p>同源重组缺陷（Homologous Recombination Deficiency, HRD）是一种广泛存在于多种肿瘤中的基因组不稳定性特征。当细胞的DNA损伤修复通路，特别是同源HRD，对PARP抑制剂高度敏感。部分突变类型也可预测对铂类化疗敏感。</td>
<td style="padding:12px;border-bottom:2px solid #d9d9d9;border-right:2px solid #d9d9d9;line-height:1.6;">奥拉帕利、尼拉帕利、卢卡帕利、他拉唑帕利</td>
的结构变异特征</td>
<td style="padding:12px;border-bottom:2px solid #d9d9d9;border-right:2px solid #d9d9d9;line-height:1.6;">独立于BRCA1/2突变，反映基因组整体的HRD状态，是预测PARP抑制剂疗效的重要生物标志物。</td>
<td style="padding:12px;border-bottom:2px solid #d9d9d9;border-right:2px solid #d9d9d9;line-height:1.6;">奥拉帕利多种变异类型；能够提供定量的HRD评分，更精准地评估HRD状态；灵敏度高，对低丰度突变也能有效检出；可同时分析多个基因和生物标志物，实现
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<tr><td>肿瘤同源重组缺陷（HRD）</td><td>¥9152</td><td><strong>¥7040</strong></td></tr>
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